“Pique, a***hole, Spain is your country…. Pique, a***hole, leave the national team,” chanted fans, while others should “son of a b****” at the former Manchester United defender.
Others held up signs saying ‘Pique fora’ – “Pique out”, while one loan supporter held up a message on their mobile declaring ‘Pique T’estimo’ – “Pique I love you”.
Speaking after the win over Las Palmas on Sunday, Pique said about the referendum: “You vote yes, no, or leave it blank, but you vote. In the Franco era, we couldn’t defend our ideas.
“I am, and I feel Catalan, and I am very proud of the people, of their behaviour, like in the last seven years.
“After what has transpired it has been my worst experience as a professional. It has been a tough day. There were families, children and grandparents, and the police and Guardia Civil have intervened.
“The people protested without violence. I thought they would try to stop the vote in a peaceful way. Everyone has seen what happened. They’ve made things worse.
“This is among the worst decisions in the last 50 years. They’ve separated Catalonia from Spain even more and there will be consequences.”
Pique, who has 91 caps for his country, called Barcelona’s behind-closed-doors win over Las Palmas on Sunday “my worst experience as a professional”.